Calcipotriol Monohydrate

Product Description

Packaging Size 25 kg

Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D3).Binding of calcipotriol (hydrate) to the VDR increases AP-1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response.Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-cell differentiation in keratinocytes.

 Specification:

• Formal Name: 24-cyclopropyl-(1,3,5Z,7E,22E,24S)-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol, monohydrate
• CAS Number :112828-00-9
• Synonyms : Calcipotriene
• Molecular Formula : C27H40O3 H2O
• Formula Weight :412.6
• Purity: 98%
• Formulation A crystalline solid
• Product Type: API